BioLiP

>8avyA (length=1175) Species: 10090 (Mus musculus) [Search protein sequence]

SVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGQ
VSKQSTQMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWA
LAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIG
DKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILS
SFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRL
GIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFS
VCIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDN
IQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGGGKSTTV
QLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAEN
IRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQ
RIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAH
RLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTEDVPPASFW
RILKLNSTEWPYFVVGIFAAIINGGLQPAFSVIFSKVVGVFTNGGPPETQ
RQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLR
QDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGII
ISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIAT
EAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAM
MYFSYAAAFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDY
AKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRP
SIPVLQGLSLEVKKGQTLALVGSSGGGKSTVVQLLERFYDPMAGSVFLDG
KEIKQLNVQWLRAQLGIVSQEPILFDRSIAENIAYGDNSRVVSYEEIVRA
AKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILL
LDEATSALDTESEKVVQEALDKAREGRTVIVIAHRLSTIQNADLIVVIQN
GKVKEHGTHQQLLAQKGIYFSMVSV

	Biological Process
GO:0001666	response to hypoxia
GO:0001890	placenta development
GO:0007565	female pregnancy
GO:0007595	lactation
GO:0007623	circadian rhythm
GO:0009410	response to xenobiotic stimulus
GO:0009914	hormone transport
GO:0010046	response to mycotoxin
GO:0014070	response to organic cyclic compound
GO:0031667	response to nutrient levels
GO:0032355	response to estradiol
GO:0032496	response to lipopolysaccharide
GO:0032570	response to progesterone
GO:0033189	response to vitamin A
GO:0033280	response to vitamin D
GO:0033762	response to glucagon
GO:0035633	maintenance of blood-brain barrier
GO:0036146	cellular response to mycotoxin
GO:0043215	daunorubicin transport
GO:0045332	phospholipid translocation
GO:0046686	response to cadmium ion
GO:0046865	terpenoid transport
GO:0050892	intestinal absorption
GO:0055085	transmembrane transport
GO:0060856	establishment of blood-brain barrier
GO:0071217	cellular response to external biotic stimulus
GO:0071222	cellular response to lipopolysaccharide
GO:0071236	cellular response to antibiotic
GO:0071312	cellular response to alkaloid
GO:0071356	cellular response to tumor necrosis factor
GO:0071392	cellular response to estradiol stimulus
GO:0071475	cellular hyperosmotic salinity response
GO:0071548	response to dexamethasone
GO:0071549	cellular response to dexamethasone stimulus
GO:0097068	response to thyroxine
GO:0097305	response to alcohol
GO:0097327	response to antineoplastic agent
GO:0099040	ceramide translocation
GO:0140115	export across plasma membrane
GO:1902065	response to L-glutamate
GO:1902396	protein localization to bicellular tight junction
GO:1903416	response to glycoside
GO:1904057	negative regulation of sensory perception of pain
GO:1904148	cellular response to nonylphenol
GO:1904446	positive regulation of establishment of Sertoli cell barrier
GO:1904478	regulation of intestinal absorption
GO:1905231	cellular response to borneol
GO:1905232	cellular response to L-glutamate
GO:1905233	response to codeine
GO:1905235	response to quercetin
GO:1905237	response to cyclosporin A
GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane
GO:1990962	xenobiotic transport across blood-brain barrier
GO:1990963	establishment of blood-retinal barrier
GO:2001025	positive regulation of response to drug

	Cellular Component
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016324	apical plasma membrane
GO:0031526	brush border membrane
GO:0045177	apical part of cell
GO:0046581	intercellular canaliculus

PDB	RCSB:8avy, PDBe:8avy, PDBj:8avy
PDBsum	8avy
PubMed	38259172
UniProt	P21447\|MDR1A_MOUSE ATP-dependent translocase ABCB1 (Gene Name=Abcb1a)

Structure of PDB 8avy Chain A