Structure of PDB 8avx Chain A

Receptor sequence
>8avxA (length=480) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence]
ENCEREPIHIPGSIQPHGALLTADGHSGEVLQMSLNAATFLGQEPTVLRG
QTLAALLPEQWPALQAALPPGCPDALQYRATLDWPAGHLSLTVHRVGELL
ILEFEPTEHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFA
PDATGEVIAEARREGLHAFLGHRFPASDIPAQARALYTRHLLRLTADTRA
AAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVV
GGQLWGLIACHHQTPYVLPPDLRTTLEYLGRLLSLQVQVKEAADVAAFRQ
SLREHHARVALAAAHSLSPHDTLSDPALDLLGLMRAGGLILRFEGRWQTL
GEVPPAPAVDALLAWLETQPGALVQTDALGQLWPAGADLAPSAAGLLAIS
VGEGWSECLVWLRPELRLEVAWGPRHSFDTYLEEKRGYAEPWHPGEIEEA
QDLRDTLTGALGERLSVIRDLNRALTQSNA
3D structure
PDB8avx Structural mechanism of signal transduction in a phytochrome histidine kinase.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLA A C24 D207 I208 Y216 R222 R254 H260 Y263 M267 L286 C3 D178 I179 Y187 R193 R225 H231 Y234 M238 L257
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0000156 phosphorelay response regulator activity
GO:0004673 protein histidine kinase activity
GO:0005524 ATP binding
GO:0009881 photoreceptor activity
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0030295 protein kinase activator activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
GO:0007165 signal transduction
GO:0007234 osmosensory signaling via phosphorelay pathway
GO:0009584 detection of visible light
GO:0016310 phosphorylation
GO:0018106 peptidyl-histidine phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8avx, PDBe:8avx, PDBj:8avx
PDBsum8avx
PubMed36509762
UniProtQ9RZA4|BPHY_DEIRA Bacteriophytochrome (Gene Name=bphP);
Q9RZA5

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