Structure of PDB 8as0 Chain A

Receptor sequence
>8as0A (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
RPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKL
AAFPEQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIK
ESLRAELRVTE
3D structure
PDB8as0 Selection of a PD-1 blocking antibody from a novel fully human phage display library.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A R96 V111 R61 V76
BS02 FUC A E61 Q99 E32 Q64
Gene Ontology
Biological Process
GO:0050777 negative regulation of immune response
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8as0, PDBe:8as0, PDBj:8as0
PDBsum8as0
PubMed36317676
UniProtQ15116|PDCD1_HUMAN Programmed cell death protein 1 (Gene Name=PDCD1)

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