Structure of PDB 8aoq Chain A

Receptor sequence
>8aoqA (length=105) Species: 55518 (Magnetospirillum gryphiswaldense) [Search protein sequence]
ASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLR
LIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRL
AEGPA
3D structure
PDB8aoq Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines.
ChainA
Resolution2.088 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C24 C27 C90 C93 C6 C9 C72 C75
BS02 N8F A N50 F77 S78 W79 W85 W99 Y101 N32 F59 S60 W61 W67 W81 Y83
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8aoq, PDBe:8aoq, PDBj:8aoq
PDBsum8aoq
PubMed36476642
UniProtA4TVL0

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