Structure of PDB 8alk Chain A

Receptor sequence
>8alkA (length=447) Species: 446 (Legionella pneumophila) [Search protein sequence]
MDKIITGKKIIFSQSVAKDQTKNLSSFLSERFYSVNQSHNHSIIIGSSLS
HQENDIEHDTILDTSGVLVTTDTNGIVNGARVAITDGLGGGDQEEDDEIY
RVSHSSCENFLNSDQNIDTTLSLITQHTEASMAAFIYQNHPGKGYIGEFA
NIGDGLIIILDKRFKIKHMVSASHIYRGFGTWTPPSLQALATTANKDALL
VRQTLKLAEGDIIISMTDGVWGELKTSLIAQTNDRRDIGVDKEYFKTLFD
ELTDAPYPSSFDIARIITQRAMSRSLERRKTLIKLINEIEQQHFHEKSVK
TINEVLEYFIKTGHVETAQTLKAILFEDGLSDGITYFENIEIPLEMVMHD
LKSRCVGDCSTINVTRIPYHLDELIRGFINYPEKHQILAPLFKARVKSEA
DLEEAFHRLSLEMVQPEIESPISETHFERAFKKETLDKTQAVLTHYF
3D structure
PDB8alk Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D105 D254 D394 D86 D218 D358
BS02 CA A D105 G106 D86 G87
BS03 CA A D190 D254 D154 D218
External links
PDB RCSB:8alk, PDBe:8alk, PDBj:8alk
PDBsum8alk
PubMed37076474
UniProtQ5ZXN5|LEM3_LEGPH Phosphocholine hydrolase Lem3 (Gene Name=lem3)

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