Structure of PDB 8age Chain A

Receptor sequence
>8ageA (length=644) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SCVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRAT
KYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWL
GLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPG
YISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMV
SAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPF
VGFLPIRSNDHMAALGVFGLIQIVAFGDFVKGQIPIIASVSEHQPVSWPA
FFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSVLCSYFAGVMVRLMLT
LTPVICVSAAVALSKIFDIYLDFKKPAALLAKLIVSGSFIFYLYLFVFHS
TWVTRTAYSSPSVVLPSLIDDFREAYYWLRMNSDEDSKVAAWWDYGYQIG
GMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDYVLVIFG
GLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDARASETM
RNSLLYKMSYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYFDEVFTSEN
WMVRIYQLKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV
3D structure
PDB8age Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.99.18: dolichyl-diphosphooligosaccharide--protein glycotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S347 V348 S349 W516 W517 D518 N535 W589 S289 V290 S291 W442 W443 D444 N461 W515
BS02 CPL A L33 R112 N113 L117 L28 R107 N108 L112
BS03 MG A D47 D166 D42 D161
BS04 KZB A F258 R262 F253 R257
BS05 KZB A L58 F63 T92 W98 H99 L53 F58 T87 W93 H94
BS06 CPL A I29 L33 I24 L28
BS07 CPL A F202 Y203 F197 Y198
BS08 323 A F361 S476 F303 S410
Gene Ontology
Molecular Function
GO:0004576 oligosaccharyl transferase activity
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006486 protein glycosylation
GO:0006487 protein N-linked glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8age, PDBe:8age, PDBj:8age
PDBsum8age
PubMed36435935
UniProtP39007|STT3_YEAST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Gene Name=STT3)

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