Structure of PDB 8a8x Chain A

Receptor sequence
>8a8xA (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
HHMVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA
SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLN
GGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRV
NFQERVFPLFSVCSTGTYLRIWP
3D structure
PDB8a8x TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
ChainA
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N42 T43 R44 A69 F85 S158 C160 N45 T46 R47 A72 F88 S161 C163
External links
PDB RCSB:8a8x, PDBe:8a8x, PDBj:8a8x
PDBsum8a8x
PubMed35893676
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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