Structure of PDB 8a7h Chain A

Receptor sequence
>8a7hA (length=362) Species: 160488,224911 [Search protein sequence]
MINAKLLQLMVEHSNDGIVVAEQEGNESILIYVNPAFERLTGYCADDILY
QDCRFLQGEDHDQPGRAIIREAIREGRPCCQVLRNYRKDGSLFWNELSIT
PVHNEADQLTYYIGIQRDVTEHQQTQARLQELQSELVHVSRLSAMGEMAS
ALAHELNQPLAAISNYMKGSRRLLAGSSDPNTPKVESALDRAAEQALRAG
QIIRRLRDFVARGESEKRVESLSKLIEEAGALGLAGAREQNVQLRFSLDP
GADLVLADRVQIQQVLVNLFRNALEAMAQSQRRELVVTNTPAADDMIEVE
VSDTGSGFQDDVIPNLFQTFFTTKDTGMGVGLSISRSIIEAHGGRMWAES
NASGGATFRFTL
3D structure
PDB8a7h Crystal structure of a chimeric LOV-Histidine kinase SB2F1-I66R mutant (light state; asymmetrical variant, trigonal form with long c axis)
ChainA
Resolution3.145 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A N272 F308 L316 T323 K324 G327 M328 G329 G331 L332 F358 N272 F308 L316 T323 K324 G327 M328 G329 G331 L332 F358
BS02 JGC A C53 R54 L56 R66 R70 N85 N95 L97 I99 Y112 Q116 C53 R54 L56 R66 R70 N85 N95 L97 I99 Y112 Q116
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

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Molecular Function

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Biological Process
External links
PDB RCSB:8a7h, PDBe:8a7h, PDBj:8a7h
PDBsum8a7h
PubMed
UniProtP23222|FIXL_BRADU Sensor protein FixL (Gene Name=fixL);
Q88JB0

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