Structure of PDB 8a7f Chain A

Receptor sequence
>8a7fA (length=363) Species: 160488,224911 [Search protein sequence]
HMINAKLLQLMVEHSNDGIVVAEQEGNESILIYVNPAFERLTGYCADDIL
YQDCRFLQGEDHDQPGRAIIREAIREGRPCCQVLRNYRKDGSLFWNELSI
TPVHNEADQLTYYIGIQRDVTEHQQTQARLQELQSELVHVSRLSAMGEMA
SALAHELNQPLAAISNYMKGSRRLLAGSSDPNTPKVESALDRAAEQALRA
GQIIRRLRDFVARGESEKRVESLSKLIEEAGALGLAGAREQNVQLRFSLD
PGADLVLADRVQIQQVLVNLFRNALEAMAQSQRRELVVTNTPAADDMIEV
EVSDTGSGFQDDVIPNLFQTFFTTKDTGMGVGLSISRSIIEAHGGRMWAE
SNASGGATFRFTL
3D structure
PDB8a7f Crystal structure of a chimeric LOV-Histidine kinase SB2F1-I66R mutant (asymmetrical variant, trigonal form with long c axis)
ChainA
Resolution2.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A N268 N272 F308 L316 T322 T323 M328 V330 G331 L332 A356 F358 N269 N273 F309 L317 T323 T324 M329 V331 G332 L333 A357 F359
BS02 FMN A V19 D52 C53 R54 L56 Q57 R66 R70 N85 N95 L97 I99 G114 Q116 V20 D53 C54 R55 L57 Q58 R67 R71 N86 N96 L98 I100 G115 Q117
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

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Molecular Function

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Biological Process
External links
PDB RCSB:8a7f, PDBe:8a7f, PDBj:8a7f
PDBsum8a7f
PubMed
UniProtP23222|FIXL_BRADU Sensor protein FixL (Gene Name=fixL);
Q88JB0

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