Structure of PDB 8a73 Chain A

Receptor sequence
>8a73A (length=344) Species: 80249 (Phaedon cochleariae) [Search protein sequence]
FSKEESREFMAIFPDIVRDLTDAGRHTDIPEVTKRFAKVLQYNVPTGKKT
RGLSTVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDRS
ETRRGQPCWYRQENVGFLAINDCLHVESSLYSVLRKYFSHLPCYVPIIEL
FHDVNFKTNMGQSLDALCMKDGRPILSQFTMKRYSSIVKYKTSYYTFQLP
VSLGMYLADMYDPEQHRQAKTILMEIGEFFQIQDDFLDAFGDSQVTGKVG
TDIKEGKCSWLAVVALQRSNPAQRQIMEEHYGRPEPESTQIIKNLYIELG
LPATFAVYEEESFNIIRTHIHQISKGLPHDLFFKIMKKIYKRDA
3D structure
PDB8a73 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.1: dimethylallyltranstransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D179 D183 D94 D98
BS02 MN A D179 D183 D94 D98
BS03 GPP A K133 T135 R136 S139 R189 T281 F315 K48 T50 R51 S54 R104 T196 F230
BS04 GPP A L175 M178 D179 R188 N244 Q247 K276 Y280 K342 L90 M93 D94 R103 N159 Q162 K191 Y195 K257
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8a73, PDBe:8a73, PDBj:8a73
PDBsum8a73
PubMed37308711
UniProtM1JS91

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