Structure of PDB 8a56 Chain A

Receptor sequence

>8a56A (length=538) Species: 1351 (Enterococcus faecalis)

GKIVIIGGVAGGMSAATRLRRLMEDAEIVVMEKGPFVSFANCGLPYYVSG
EIAEREQLLVQTPEALKARFNLDVRPHHEVVAIDPIEKVITVKHETEILT
EHYDKLILSPGAKPFVPPITGLAEAKNVFSLRNVPDLDQIMTALTPETKR
AVVIGAGFIGLEMAENLQKRGLEVTLVEKAPHVLPPLDEEMAAFVKAELS
KNNVQVITGQSAVAFEEEGQVIRLEDGQTLASDLTILSVGVQPENTLAVE
AGVATGLRGGIVVDEHYQTNQPDIYAVGDAIVVKQQITQEDALISLASPA
NRQGRQVADVIAGLERKNQGSIGTAIVRVFDLTAASTGLSERAAKAAGLT
TAVVHISGKDHAGYYPGATDLQLKLVFHPTTGEIYGAQGIGAKGVDKRID
ILATAIKGQLTIFDLPELEFTYAPPFGSAKDPVNMLGYAAMNLVEGLSEN
VQWYELSNELAKGAVLLDVRNPAQFKNAVSIPLNELRERLEELDKSTEYI
VSCHSGLRSYIAERMLKQAGISAKNLDGAFALYRMVKP

3D structure

• PDB: 8a56 Metabolic and Structural Insights into Hydrogen Sulfide Mis-Regulation in Enterococcus faecalis.
• Chain: A
• Resolution: 2.05 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G7 V9 A10 E32 K33 N41 C42 V80 S109 P110 G111 G278 D279 L296 A297	G7 V9 A10 E32 K33 N41 C42 V80 S109 P110 G111 G278 D279 L296 A297
BS02	PAP	A	T17 R18 R21 F70 R305	T17 R18 R21 F70 R305
BS03	PAP	A	I356 K430 M435 Y438 G511 L512 Y515	I356 K430 M435 Y438 G506 L507 Y510
BS04	FAD	A	Y422 A423	Y422 A423

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity

External links

• PDB: RCSB:8a56, PDBe:8a56, PDBj:8a56
• PDBsum: 8a56
• PubMed: 36009332
• UniProt: Q82ZQ9