Structure of PDB 8a3h Chain A

Receptor sequence
>8a3hA (length=300) Species: 76935 (Salipaludibacillus agaradhaerens) [Search protein sequence]
SVVEEHGQLSISNGELVNERGEQVQLKGMSSHGLQWYGQFVNYESMKWLR
DDWGINVFRAAMYTSSGGYIDDPSVKEKVKEAVEAAIDLDIYVIIDWHIL
SDNDPNIYKEEAKDFFDEMSELYGDYPNVIYEIANEPNGSDVTWGNQIKP
YAEEVIPIIRNNDPNNIIIVGTGTWSQDVHHAADNQLADPNVMYAFHFYA
GTHGQNLRDQVDYALDQGAAIFVSEWGTSAATGDGGVFLDEAQVWIDFMD
ERNLSWANWSLTHKDESSAALMPGANPTGGWTEAELSPSGTFVREKIRES
3D structure
PDB8a3h Lateral Protonation of a Glycosidase Inhibitor. Structure of the Bacillus agaradhaerens Cel5A in Complex with a Cellobiose-Derived Imidazole at 0.97 A Resolution
ChainA
Resolution0.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IDC A H35 Y66 H101 L103 E139 Y202 E228 A234 T235 G236 W262 K267 E269 H32 Y63 H98 L100 E136 Y199 E225 A231 T232 G233 W259 K264 E266 MOAD: Ki=88uM
PDBbind-CN: -logKd/Ki=4.06,Ki=88uM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8a3h, PDBe:8a3h, PDBj:8a3h
PDBsum8a3h
PubMed
UniProtO85465|GUN5_SALAG Endoglucanase 5A (Gene Name=cel5A)

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