Structure of PDB 8a1h Chain A

Receptor sequence

>8a1hA (length=516) Species: 666 (Vibrio cholerae)

MRYSVVRLILGDQLNHAHSWFSEHRDDVLYLIAELHQEQEYVRHHIQKQC
AFFAAMQAFADYLSAEGHHVWHLDLDASAQYNDLPDLIAQICQQVQADAF
QYQRPDEYRLLEQMANLRLSGITIGCVDTEHFLLPFAEIPEQFPASKAVL
MEHFYRRMRKRFGYLMTADGKPEGGQWNFDADNRNKLKSPDLLQLPTPLC
FDNPVASIKARIERHRIPSIGQVGESLLWPINRAQALSLLAHFCQICLPN
FGRFQDAMTAQHPHRWSLYHSRLSFALNSKLLSPREVIEATISAYRAAQG
QISLAQVEGFVRQILGWREYVRGMYWSNMPHYQTRNHLGAQRPLPSYFWN
GQTKMRCLQQAITQSLDFGYAHHIQRLMVTGNFALLTECDPDQVDAWYLG
IYIDAIEWVELPNTRGMALFADGGLIATKPYSASGSYINKMSDYCASCAY
QVKLKSGEKACPLNSLYWRFMLKHRDRLANNPRIGMLYKTWDKMTSDSQQ
AILSTADAYLSQIESL

3D structure

• PDB: 8a1h Structural and Functional Analysis of a Prokaryotic (6-4) Photolyase from the Aquatic Pathogen Vibrio Cholerae † .
• Chain: A
• Resolution: 1.65 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	F271 H290 S291 R292 S294 N298 Q333 I334 R338 Y390 H393 R396 L397 Y418 D424 A425 V429 E430 N433 T434	F251 H270 S271 R272 S274 N278 Q313 I314 R318 Y370 H373 R376 L377 Y398 D404 A405 V409 E410 N413 T414
BS02	DLZ	A	L30 G31 D32 A53 E54 L55 E58 Q59 Y61 H64 F72 M76 D126 E127 I426	L10 G11 D12 A33 E34 L35 E38 Q39 Y41 H44 F52 M56 D106 E107 I406
BS03	SF4	A	M375 C377 I458 Y464 C465 C468 V472 C481	M355 C357 I438 Y444 C445 C448 V452 C461

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003674 molecular_function
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0008150 biological_process

Cellular Component

• GO:0005575 cellular_component

External links

• PDB: RCSB:8a1h, PDBe:8a1h, PDBj:8a1h
• PDBsum: 8a1h
• PubMed: 36692077
• UniProt: Q9KLD7