Structure of PDB 7zy4 Chain A

Receptor sequence
>7zy4A (length=305) Species: 9606 (Homo sapiens) [Search protein sequence]
QEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDI
WYEAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLY
FAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKS
GRMIFKKAREDTRTRHHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDI
PEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFES
NIGDLASILKVEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELKA
LGYKD
3D structure
PDB7zy4 Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R395 K399 R402 V428 K431 L435 R152 K156 R159 V185 K188 L192
Gene Ontology
Biological Process
GO:0006396 RNA processing
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:7zy4, PDBe:7zy4, PDBj:7zy4
PDBsum7zy4
PubMed36073787
UniProtQ12996|CSTF3_HUMAN Cleavage stimulation factor subunit 3 (Gene Name=CSTF3)

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