Structure of PDB 7zwz Chain A

Receptor sequence
>7zwzA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
ADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACS
GLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMA
VMATAMYLQMEHVVDTCRKFIKASE
3D structure
PDB7zwz Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays.
ChainA
Resolution1.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I9 Q10 F11 T12 I5 Q6 F7 T8
BS02 K6I A M51 A52 C53 S54 G55 Y58 Q113 E115 H116 M47 A48 C49 S50 G51 Y54 Q109 E111 H112
External links
PDB RCSB:7zwz, PDBe:7zwz, PDBj:7zwz
PDBsum7zwz
PubMed36329085
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

[Back to BioLiP]