Structure of PDB 7zwr Chain A

Receptor sequence
>7zwrA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
SCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGL
FYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVM
ATAMYLQMEHVVDTCRKFIKASE
3D structure
PDB7zwr Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays.
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I9 Q10 F11 T12 I3 Q4 F5 T6
BS02 K4X A M51 A52 Y58 M45 A46 Y52
External links
PDB RCSB:7zwr, PDBe:7zwr, PDBj:7zwr
PDBsum7zwr
PubMed36329085
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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