Structure of PDB 7zwo Chain A

Receptor sequence
>7zwoA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
ADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACS
GLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMA
VMATAMYLQMEHVVDTCRKFIKASE
3D structure
PDB7zwo Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays.
ChainA
Resolution1.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I9 Q10 F11 T12 I5 Q6 F7 T8
BS02 KCB A M51 A52 C53 G55 Y58 Q113 M47 A48 C49 G51 Y54 Q109
External links
PDB RCSB:7zwo, PDBe:7zwo, PDBj:7zwo
PDBsum7zwo
PubMed36329085
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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