Structure of PDB 7zvs Chain A

Receptor sequence
>7zvsA (length=300) Species: 6183 (Schistosoma mansoni) [Search protein sequence]
NRTRKPFEELCTELADLDMPAENIVLNRRVGQGAFGLVFGGEAKKSDLWE
AVAVKVINEKANYEGKIDFLSEAKLMRSLNHPNVVRLIGISLNPKASLYL
IMELMLLGDLKTYLLSRRILAQRSPNHEDIRPSTLTQMSMDIGQGLAYLH
SKHLIHRDIACRNCLVAADRTVKIGDFGLTRQAALPIRWMSPEAVQFGVF
SIQSDIWSFGITLYEIITFGVFPYNGLGDVEVVERVKRMEFSITEFLPPQ
ALNTVVCELINHCCKHQWQHRPSSMNQVLEVLIAYPDCIRPFLTDDPPKP
3D structure
PDB7zvs Identification of Inhibitors of the Schistosoma mansoni VKR2 Kinase Domain.
ChainA
Resolution3.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A V972 G975 A976 V980 A995 K997 M1047 N1105 L1107 D1118 V30 G33 A34 V38 A53 K55 M105 N163 L165 D176
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7zvs, PDBe:7zvs, PDBj:7zvs
PDBsum7zvs
PubMed36385939
UniProtA0A3Q0KQ92

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