Structure of PDB 7zvj Chain A

Receptor sequence
>7zvjA (length=583) Species: 9606 (Homo sapiens) [Search protein sequence]
KCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILA
TLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPA
NLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLPW
PALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIF
NAVIKQNPFLVYQLPCFWNVQLSQCVSDLKVIHWNKHVEFFRNLYLTFLE
YDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRT
HLYFLHYEYEPAADSTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLS
DAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQFYPVNLLRNVAMKHIST
PYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSF
PKSKAELLSMLDMGTLFTFTNFAKWRTATTPYRVEWEADFEPYVVVRRDC
PEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKF
NKQYRICLKTLKEEFQQDMSRRYGFAALKYLTA
3D structure
PDB7zvj Structural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase.
ChainA
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.-.-
2.4.1.-
2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D565 H705 H708 D409 H538 H541
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7zvj, PDBe:7zvj, PDBj:7zvj
PDBsum7zvj
PubMed36512577
UniProtO95461|LARG1_HUMAN Xylosyl- and glucuronyltransferase LARGE1 (Gene Name=LARGE1)

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