Structure of PDB 7zu1 Chain A

Receptor sequence
>7zu1A (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNANSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRSCSRRFYQLTKLLDSVQPIARELH
QFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB7zu1 A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
ChainA
Resolution1.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DHT A L705 N706 M746 M750 F765 T878 L34 N35 M75 M79 F94 T203
External links
PDB RCSB:7zu1, PDBe:7zu1, PDBj:7zu1
PDBsum7zu1
PubMed36921044
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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