Structure of PDB 7ztz Chain A

Receptor sequence
>7ztzA (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLCFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACSCSRRFYQLTKLLDSVQPIARELHQF
TFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB7ztz A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DHT A L702 L705 N706 Q712 M750 F765 T878 M896 L31 L34 N35 Q41 M79 F94 T201 M219
External links
PDB RCSB:7ztz, PDBe:7ztz, PDBj:7ztz
PDBsum7ztz
PubMed36921044
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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