Structure of PDB 7ztx Chain A

Receptor sequence
>7ztxA (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSVTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACSCSRRFYQLTKLLDSVQPIARELHQF
TFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB7ztx A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
ChainA
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DHT A L705 N706 Q712 M746 M750 F765 T878 L34 N35 Q41 M75 M79 F94 T201
External links
PDB RCSB:7ztx, PDBe:7ztx, PDBj:7ztx
PDBsum7ztx
PubMed36921044
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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