Structure of PDB 7ztv Chain A

Receptor sequence
>7ztvA (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSLTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACSCSRRFYQLTKLLDSVQPIARELHQF
TFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB7ztv A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
ChainA
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DHT A L705 N706 L708 Q712 M746 M750 F765 T878 L34 N35 L37 Q41 M75 M79 F94 T201
External links
PDB RCSB:7ztv, PDBe:7ztv, PDBj:7ztv
PDBsum7ztv
PubMed36921044
UniProtP15207|ANDR_RAT Androgen receptor (Gene Name=Ar)

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