Structure of PDB 7zpy Chain A

Receptor sequence
>7zpyA (length=438) Species: 641809 (Influenza A virus (A/California/07/2009(H1N1))) [Search protein sequence]
SIEPFLRTTPRPLRLPDGPLCHQRSKFLLMDALKLSIEDPSHEGEGIPLY
DAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIENEEKIP
RTKNMKRTSQLKWALGENMAPEKSDEPEPRSLASWVQNEFNKACELTDSS
WIELDEIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMD
DFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLT
DPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWG
MEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPRGV
EEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEP
GTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
3D structure
PDB7zpy Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q408 N412 C415 E617 W619 P620 I621 G622 E623 K635 T639 L666 Q670 R673 N703 W706 F710 Q137 N141 C144 E339 W341 P342 I343 G344 E345 K357 T361 L388 Q392 R395 N425 W428 F432
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7zpy, PDBe:7zpy, PDBj:7zpy
PDBsum7zpy
PubMed36265804
UniProtC3W5X6

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