Structure of PDB 7zo2 Chain A

Receptor sequence
>7zo2A (length=265) Species: 40324 (Stenotrophomonas maltophilia) [Search protein sequence]
VPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLL
DGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGA
KVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVF
TAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHL
IEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADA
AEQKFDGQLAKETAG
3D structure
PDB7zo2 Interactions of hydrolyzed beta-lactams with the L1 metallo-beta-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D88 H89 H225 D86 H87 H223
BS02 ZN A H84 H86 H160 H82 H84 H158
BS03 DQM A Y11 H84 H86 D88 F124 H160 S185 S187 P189 H225 G227 A228 Y9 H82 H84 D86 F122 H158 S183 S185 P187 H223 G225 A226
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic
Cellular Component
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:7zo2, PDBe:7zo2, PDBj:7zo2
PDBsum7zo2
PubMed36924941
UniProtP52700|BLA1_STEMA Metallo-beta-lactamase L1 type 3

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