Structure of PDB 7zle Chain A

Receptor sequence
>7zleA (length=284) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
SVSKTEHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLS
PSFKDFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVL
FPLSLDKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYR
FWKTGYWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPN
SLANLDQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNP
MTKEPKLDRARRQVPEWTKYDEEIAELARRVREG
3D structure
PDB7zle A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
ChainA
Resolution1.823 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 UDP A S1207 Y1211 Q1276 C1437 N1438 K1446 S17 Y21 Q86 C247 N248 K256
BS02 CA A D1302 D1304 D1435 D112 D114 D245
BS03 PDO A W1280 D1396 W90 D206
BS04 PDO A V1205 K1283 D1302 V15 K93 D112
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7zle, PDBe:7zle, PDBj:7zle
PDBsum7zle
PubMed
UniProtG0SB58

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