Structure of PDB 7ziu Chain A

Receptor sequence
>7ziuA (length=603) Species: 64292 (Ntaya virus) [Search protein sequence]
TNWKMVEDRVKKLADEFSTTWHYDSEHPYKTWNYHGSYEVKATGSASSMV
NGVVRVLSKPWDTLAMTDTTPFGQQRVFKEKVDTKAPEPPKGTAEVMRVT
AKWMWKFVGRSKTPRVCTKEEFIAKVNSHQNRWASAREAVEDPAFWEMVD
REREAHLQGRCEMCTYNMMGKREKKMGEFGKAKGSRAIWYMWLGSRYLEF
EALGFLNEDHWMSRENTLGGVEGLGLQKLGYVLRDIAKNPGGLMYADDTA
GWDTRITKADLENESIVLEMMTPEHRALAEPLIKFAYMNKVVKVMRPGAD
GITVMDVISREDQRGSGQVVTYALNTFTNLCVQLIRCMEGEGLLKPEEVE
KLERGKQRKIQDWLDKNGTERLASMAVSGDDCVVKPKDDRFATALHFLNS
MSKIRKDIPEWKQSTGWRNWQDVPFCSHHFHELTMKDGRQIVVPCRHQDE
LIGRARLSPGSGWSLTETACLSKAYGQMWLLMYFHRRDLRLMANAICSAV
PVSWVPTGRTTWSIHGKGEWMTTEDMLRVWNRVWIEENEHMEDKTPVSSW
NDVPYLGKREDSWCGSLIGHRARSTWAENIYTPIMQIRGLIGPERYVDYM
PTL
3D structure
PDB7ziu Crystal structure of Ntaya virus NS5 polymerase domain
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A E440 H444 C449 C452 E152 H156 C161 C164
BS02 ZN A H717 H719 C733 C852 H429 H431 C445 C564
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity
GO:0005524 ATP binding
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7ziu, PDBe:7ziu, PDBj:7ziu
PDBsum7ziu
PubMed38781970
UniProtK0BRZ6

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