Structure of PDB 7zhb Chain A

Receptor sequence
>7zhbA (length=286) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
SVSKTEHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLS
PSFKDFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVL
FPLSLDKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYR
FWKTGYWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPN
SLANLDQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNP
MTKEPKLDRARRQVPEWTKYDEEIAELARRVREGTK
3D structure
PDB7zhb A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
ChainA
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UPG A A1206 S1207 Y1211 Q1276 W1280 D1302 S1359 A1360 D1396 D1435 C1437 N1438 K1446 A16 S17 Y21 Q86 W90 D112 S169 A170 D206 D245 C247 N248 K256
BS02 CA A D1302 D1304 D1435 D112 D114 D245
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7zhb, PDBe:7zhb, PDBj:7zhb
PDBsum7zhb
PubMed
UniProtG0SB58

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