Structure of PDB 7zfx Chain A

Receptor sequence
>7zfxA (length=239) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSW
SCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAI
CLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLA
DLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
3D structure
PDB7zfx Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I270 K274 R280 I288 P442 E446 E451 V452 I56 K60 R66 I74 P228 E232 E237 V238
BS02 IV1 A Y175 V262 S265 I296 R302 S303 S306 W314 C316 I325 D327 V328 H333 L338 L341 H423 Y22 V48 S51 I82 R88 S89 S92 W100 C102 I111 D113 V114 H119 L124 L127 H209
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:7zfx, PDBe:7zfx, PDBj:7zfx
PDBsum7zfx
PubMed36166643
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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