Structure of PDB 7zfg Chain A

Receptor sequence
>7zfgA (length=237) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSW
SCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAI
CLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLA
DLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSE
3D structure
PDB7zfg Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3.
ChainA
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I270 K274 R280 I288 K292 P442 E446 E451 I56 K60 R66 I74 K78 P228 E232 E237
BS02 IV5 A Y175 S265 I299 M300 R302 S303 S306 W314 C316 Y323 I325 D327 V328 H333 H423 Y22 S51 I85 M86 R88 S89 S92 W100 C102 Y109 I111 D113 V114 H119 H209
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zfg, PDBe:7zfg, PDBj:7zfg
PDBsum7zfg
PubMed36166643
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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