Structure of PDB 7zex Chain A

Receptor sequence
>7zexA (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
AGHMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHR
GFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEG
3D structure
PDB7zex RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A V7 Y9 D34 Q36 L39 D40 Y41 E44 R47 F49 F51 E53 R78 N80 A82 K83 P84 M85 I87 K88 V10 Y12 D37 Q39 L42 D43 Y44 E47 R50 F52 F54 E56 R81 N83 A85 K86 P87 M88 I90 K91
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7zex, PDBe:7zex, PDBj:7zex
PDBsum7zex
PubMed37075125
UniProtQ9UNP9|PPIE_HUMAN Peptidyl-prolyl cis-trans isomerase E (Gene Name=PPIE)

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