Structure of PDB 7ze6 Chain A

Receptor sequence

>7ze6A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDA
VKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY
NKPGDDIVLMAEALEKLFLQKINELPTEE

3D structure

PDB

7ze6 Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Chain

Resolution

1.04 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	1P8	A	P82 N140	P43 N101

External links

PDB	RCSB:7ze6, PDBe:7ze6, PDBj:7ze6
PDBsum	7ze6
PubMed	36367089
UniProt	O60885\|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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