Structure of PDB 7zdd Chain A

Receptor sequence
>7zddA (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
DPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRD
IGKPEVEYDCDGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYK
IIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEV
AQAGKAVALYFEDKLTEIYSDRTFAP
3D structure
PDB7zdd Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 alpha and TRIM33 beta Bromodomains.
ChainA
Resolution1.625 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D884 N886 E887 D888 W889 G896 G897 L899 L900 C901 P922 S923 G924 D1 N3 E4 D5 W6 G13 G14 L16 L17 C18 P39 S40 G41
BS02 ZN A C902 C905 C928 C931 C19 C22 C45 C48
BS03 ZN A C890 C893 H910 C913 C7 C10 H27 C30
External links
PDB RCSB:7zdd, PDBe:7zdd, PDBj:7zdd
PDBsum7zdd
PubMed36098557
UniProtQ9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (Gene Name=TRIM33)

[Back to BioLiP]