Structure of PDB 7zbv Chain A

Receptor sequence
>7zbvA (length=390) Species: 1498 (Hathewaya histolytica) [Search protein sequence]
DKFLDDAEKHYLPKTYTFDNGTFIIRAGDKVSEEKIKRLYWASREVKSQF
HRVVGNDKALEVGNADDVLTMKIFNSPEEYKFNTNINGVSTDNGGLYIEP
RGTFYTYERTPQQSIFSLEELFRHEYTHYLQARYLVDGLWGQGPFYEKNR
LTWFDEGTAEFFAGSTRTSGVLPRKLILGYLAKDKVDHRYSLKKTLNSGY
DDSDWMFYNYGFAVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSD
DANKNTEYQNHIQELVDKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKA
ASLTNTSVTAEKSQYFNTFTLRGTYTGETSKGEFKDWDEMSKKLDGTLES
LAKNSWSGYKTLTAYFTNYRVTSDNKVQYDVVFHGVLTDN
3D structure
PDB7zbv Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H523 H527 E555 H124 H128 E156
BS02 ITO A N492 G493 G494 F515 L520 H523 E524 E555 E559 R573 Y607 N93 G94 G95 F116 L121 H124 E125 E156 E160 R174 Y208
BS03 CA A E498 A531 V535 G537 E99 A132 V136 G138
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zbv, PDBe:7zbv, PDBj:7zbv
PDBsum7zbv
PubMed36154055
UniProtQ9X721|COLG_HATHI Collagenase ColG (Gene Name=colG)

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