Structure of PDB 7z9f Chain A

Receptor sequence
>7z9fA (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSRIQVRL
GEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSR
3D structure
PDB7z9f Structural Basis of the Pancreatitis-Associated Autoproteolytic Failsafe Mechanism in Human Anionic Trypsin.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.4: trypsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E75 N77 V80 E85 E52 N54 V57 E62
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7z9f, PDBe:7z9f, PDBj:7z9f
PDBsum7z9f
PubMed35775010
UniProtP07478|TRY2_HUMAN Trypsin-2 (Gene Name=PRSS2)

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