Structure of PDB 7z5z Chain A

Receptor sequence
>7z5zA (length=337) Species: 1629 (Weissella viridescens) [Search protein sequence]
PVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQ
GAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDG
RAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVADAGMHATIQPRLNMVL
DLTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYT
TMAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGR
KIWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDS
LYVFKHVFVKDAPREYIGEIDKVLDPEVYAELVKDGH
3D structure
PDB7z5z Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.10: UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R205 H206 Y254 S259 P268 S300 L301 F304 K305 R205 H206 Y254 S259 P268 S300 L301 F304 K305
BS02 peptide A W32 K36 H139 Q143 I208 T209 R211 Y215 Y256 W32 K36 H139 Q143 I208 T209 R211 Y215 Y256
BS03 UDP A K36 W39 F70 Y103 I142 R211 K36 W39 F70 Y103 I142 R211
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016755 aminoacyltransferase activity
GO:0047206 UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0044038 cell wall macromolecule biosynthetic process
GO:0071555 cell wall organization

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7z5z, PDBe:7z5z, PDBj:7z5z
PDBsum7z5z
PubMed36350642
UniProtQ9EY50|FEMX_WEIVI UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase (Gene Name=femX)

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