Structure of PDB 7z1g Chain A

Receptor sequence
>7z1gA (length=356) Species: 9606 (Homo sapiens) [Search protein sequence]
KVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLC
DSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSKKDEVYL
NLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGIC
HRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI
FGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTR
EQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTAR
LTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILI
PPHARE
3D structure
PDB7z1g Crystal structure of nonphosphorylated (Tyr216) GSK3b kinase in complex with CX-4945
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
2.7.11.26: [tau protein] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3NG A I62 G63 N64 V70 A83 K85 V110 Y134 V135 L188 C199 D200 I36 G37 N38 V44 A57 K59 V84 Y106 V107 L160 C171 D172
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7z1g, PDBe:7z1g, PDBj:7z1g
PDBsum7z1g
PubMed
UniProtP49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta (Gene Name=GSK3B)

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