Structure of PDB 7z03 Chain A

Receptor sequence
>7z03A (length=381) Species: 562 (Escherichia coli) [Search protein sequence]
MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVF
DTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNQDSVATLNESRDIMAFL
NTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQ
QHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGLDAFPAQNFPP
ADYIALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGK
LESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTD
EYLHDIQRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEE
VFNRRLALEELDESQQQRLQHLFTTTLHTLA
3D structure
PDB7z03 Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.
ChainA
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A N14 F15 Y16 R339 N14 F15 Y16 R325
BS02 dna A N83 Q84 H222 H224 R225 K251 N83 Q84 H208 H210 R211 K237
BS03 MN A D8 H10 D48 H224 D8 H10 D48 H210
BS04 MN A D48 N83 H184 H222 D48 N83 H184 H208
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
GO:1990238 double-stranded DNA endonuclease activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006260 DNA replication
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:1990391 DNA repair complex

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Cellular Component
External links
PDB RCSB:7z03, PDBe:7z03, PDBj:7z03
PDBsum7z03
PubMed35987200
UniProtP0AG76|SBCD_ECOLI Nuclease SbcCD subunit D (Gene Name=sbcD)

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