Structure of PDB 7yxw Chain A

Receptor sequence
>7yxwA (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
IILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKGKRGWI
PASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEV
IHKLLDGWWVIRKDDVTGYFPSMYLQKS
3D structure
PDB7yxw Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W193 W204 S208 E241 D243 E244 D261 W263 Y274 M278 Y279 W38 W49 S53 E86 D88 E89 D106 W108 Y119 M123 Y124
External links
PDB RCSB:7yxw, PDBe:7yxw, PDBj:7yxw
PDBsum7yxw
PubMed
UniProtP14598|NCF1_HUMAN Neutrophil cytosol factor 1 (Gene Name=NCF1)

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