Structure of PDB 7yx8 Chain A

Receptor sequence
>7yx8A (length=440) Species: 239935 (Akkermansia muciniphila) [Search protein sequence]
GGGGPDYLYAEYRALPSPRQTGKNLRIGDGFSKYDNMTGVYLEKGRHVVL
VGKTEGQEISLLLPNLMRKPAEGVQPTKDPNGWGLHKKQIPLKEGINIID
VETPANAYISYFTEDAGKAPKIPVHFVTGKANGYFDTTRGDTNKDWVRLL
DQAVSPIMDARGKYIQVAYPVEFLKKFTKDRGTELINAYDKLIGIQYQLM
GLDKYGKIPENRVLARVNFNYYMFRDGDGVAYLGNDGTMRMVTDPENVLK
GDACWGFSHAVGHVMQMRPMTWGGMTEVSNNIFSLQAAAKTGNESRLKRQ
GSYDKARKEIIEGEIAYLQSKDVFNKLVPLWQLHLYFTKNGHPDFYPDVM
EYLRNNAGNYGGNDTVKYQFEFVKACCDVTKTDLTDFFEKWGFFKPGKFH
IGDYAQYDFNVTPEMVEETKKWIAGKGYPKPETDITELSE
3D structure
PDB7yx8 Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A P146 N147 P80 N81
BS02 peptide A Y287 Y288 F290 R291 D292 G293 H325 H329 Y470 Y221 Y222 F224 R225 D226 G227 H259 H263 Y404
BS03 GAL A G468 Y470 G402 Y404
BS04 ZN A H325 H329 E343 H259 H263 E277
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7yx8, PDBe:7yx8, PDBj:7yx8
PDBsum7yx8
PubMed35882872
UniProtB2UPI7

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