Structure of PDB 7yw4 Chain A

Receptor sequence
>7yw4A (length=120) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
VLVPITEASQLPQELIHGTNLQSVIKIIESGAISPMSRNHVHLSPGMRSS
SNVYIFIDCHSPLFFQTLKMFRSLNNVYLSSSIPVELIQKVVVKGNLKDE
EKLDTLRRILHERNIPLEKI
3D structure
PDB7yw4 Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
ChainA
Resolution2.18 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.1.160: 2'-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A H117 G118 T119 K126 I127 I133 S134 M136 R138 H142 L143 S144 M157 H17 G18 T19 K26 I27 I33 S34 M36 R38 H42 L43 S44 M47
Gene Ontology
Molecular Function
GO:0000215 tRNA 2'-phosphotransferase activity
GO:0016740 transferase activity
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0008033 tRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7yw4, PDBe:7yw4, PDBj:7yw4
PDBsum7yw4
PubMed37334830
UniProtQ12272|TPT1_YEAST tRNA 2'-phosphotransferase (Gene Name=TPT1)

[Back to BioLiP]