Structure of PDB 7yvs Chain A

Receptor sequence
>7yvsA (length=494) Species: 1496 (Clostridioides difficile) [Search protein sequence]
EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNT
AGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHAS
TDQGKTVSRATTNSKSTAVQDSNGESWNTGLSINKGESAYINANVRYYNT
GTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLA
LNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVT
EGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIG
EAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDK
KIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSAN
KLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYL
VPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELN
3D structure
PDB7yvs Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D222 D224 E231 N260 E263 D273 D6 D8 E15 N44 E47 D57
BS02 CA A D220 D222 D224 I226 E231 D4 D6 D8 I10 E15
BS03 CA A N621 D623 Q644 S646 D734 N373 D375 Q396 S398 D486
Gene Ontology
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005576 extracellular region

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7yvs, PDBe:7yvs, PDBj:7yvs
PDBsum7yvs
PubMed36253419
UniProtA8DS70

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