Structure of PDB 7yuv Chain A

Receptor sequence
>7yuvA (length=532) Species: 172827 (Meiothermus taiwanensis) [Search protein sequence]
LSDLEALRKKIEEVGMPEAVKTKALKELDRLERMQQGSPEATVARTYLDW
LTEVPWSKADPEVLDINHTRQVLDEDHYGLKDVKERILEYLAVRQLTQGL
DVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKFHRISLGGVRDEAEIRG
HRRTYIGAMPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGDPASAMLEV
LDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQTIPRPLLDRMEVIEIPG
YTNMEKQAIARQYLWPKQVRESGMEGRIEVTDAAILRVISEYTREAGVRG
LERELGKIARKGAKFWLEGAWEGLRTIDASDIPTYLGIPRYRPDKAETEP
QVGTAQGLAWTPVGGTLLTIEVAAVPGSGKLSLTGQLGEVMKESAQAALT
YLRAHTQDYGLPEDFYNKVDLHVHVPDGATPKDGPSAGITMATAIASALS
RRPARMDIAMTGEVSLRGKVMPIGGVKEKLLAAHQAGIHKIVLPKDNEAQ
LEELPKEVLEGLEIKLVEDVGEVLEYLLLPEP
3D structure
PDB7yuv A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.53: endopeptidase La.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A H319 G360 T362 S363 Y493 I501 V540 R541 H77 G118 T120 S121 Y251 I259 V298 R299
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0008236 serine-type peptidase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0030163 protein catabolic process
GO:0034605 cellular response to heat
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yuv, PDBe:7yuv, PDBj:7yuv
PDBsum7yuv
PubMed37957149
UniProtA0A059VAZ3

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