Structure of PDB 7yue Chain A

Receptor sequence

>7yueA (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSA
ISRQGSKTAYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKTT
TAFDYWGQGTLVTVSSSTDIQMTQSPSSLSASVGDRVTITCRASQSISSY
LNWYQQKPGKAPKLLIYQASALQSGVPSRFSGSGSGTDFTLTISSLQPED
FATYYCQQSHRRPLTFGQGTKVEIK

3D structure

PDB

7yue Epitope-directed anti-SARS-CoV-2 scFv engineered against the key spike protein region could block membrane fusion.

Chain

Resolution

2.35 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	I53 K59 T60 T101 T102 T103 Y166 S225 H226 R228	I51 K57 T58 T99 T100 T101 Y150 S209 H210 R212

External links

PDB	RCSB:7yue, PDBe:7yue, PDBj:7yue
PDBsum	7yue
PubMed	36691733

[Back to BioLiP]