Structure of PDB 7ysf Chain A

Receptor sequence

>7ysfA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]

PHFCPVCLRAFPYLSDLERHSISHSELKPHQCKVCGKTFKRSSHLRRHCN
IHAGLRPFRCPLCPRRFREAGELAHHHRVHSGERPYQCPICRLRFTEANT
LRRHAKRKHPEAM

3D structure

PDB

7ysf Crystal structure of ZNF524 ZF1-4 in complex with telomeric DNA

Chain

Resolution

2.4 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	R131 K140 F151 K152 R153 H156 R159 H160 R168 R177 R180 R215 K220	R19 K28 F39 K40 R41 H44 R47 H48 R56 R65 R68 R103 K108
BS02	dna	A	Y125 S127 S155 E181 G183 N211 R214	Y13 S15 S43 E69 G71 N99 R102
BS03	ZN	A	C116 C119 H132 H136	C4 C7 H20 H24
BS04	ZN	A	C144 C147 H160 H164	C32 C35 H48 H52
BS05	ZN	A	C172 C175 H188 H192	C60 C63 H76 H80
BS06	ZN	A	C200 C203 H216 H221	C88 C91 H104 H109

External links

PDB	RCSB:7ysf, PDBe:7ysf, PDBj:7ysf
PDBsum	7ysf
PubMed	38086788
UniProt	Q96C55\|ZN524_HUMAN Zinc finger protein 524 (Gene Name=ZNF524)