Structure of PDB 7ys6 Chain A

Receptor sequence
>7ys6A (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]
AALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVM
PPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILS
PLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTLKAS
LTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNP
IIYPLFMRDFKRALGRFLP
3D structure
PDB7ys6 Structural insights into constitutive activity of 5-HT 6 receptor.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SRO A D106 C110 N288 D76 C80 N221
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004993 G protein-coupled serotonin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7ys6, PDBe:7ys6, PDBj:7ys6
PDBsum7ys6
PubMed36989299
UniProtP50406|5HT6R_HUMAN 5-hydroxytryptamine receptor 6 (Gene Name=HTR6)

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