Structure of PDB 7yem Chain A

Receptor sequence

>7yemA (length=456) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]

PRGSHMNPKRIRALKSGKQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEA
NVPVVVVFCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDP
GEKISRFVKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVV
PCWEASQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPETLSDVLET
GVKALLPERALLKNKDPLFEPWHFEPGEKAAKKVMESFIADRLDSYGALR
NDPTKNMLSNLSPYLHFGQISSQRVVLEVEKAESNPGSKKAFLDEILIWK
EISDNFCYYNPGYDGFESFPSWAKESLNAHRNDVRSHIYTLEEFEAGKTH
DPLWNASQMELLSTGKMHGYTRMYWAKKILEWSESPEKALEIAICLNDRY
ELDGRDPNGYAGIAWSIGGVHDRAWGEREVTGKIRYMSYEGCKRKFDVKL
YIEKYS

3D structure

PDB

7yem Visualizing the DNA repair process by a photolyase at atomic resolution

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

4.1.99.3: deoxyribodipyrimidine photo-lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	H161 R256 E301 Y376 M379 W421 D428 W431 R441 G447 K451	H164 R250 E295 Y370 M373 W415 D422 W425 R435 G441 K445
BS02	dna	A	Y158 T162 W328 W431 G432 E433 K439	Y161 T165 W322 W425 G426 E427 K433
BS03	FAD	A	Y252 L264 S265 N266 S268 F298 E301 I302 W305 K372 R378 N403 D409 N414 G415	Y246 L258 S259 N260 S262 F292 E295 I296 W299 K366 R372 N397 D403 N408 G409

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003904	deoxyribodipyrimidine photo-lyase activity
GO:0016829	lyase activity

	Biological Process
GO:0000719	photoreactive repair
GO:0006281	DNA repair

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:7yem, PDBe:7yem, PDBj:7yem
PDBsum	7yem
PubMed	38033054
UniProt	Q8PYK9

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