Structure of PDB 7y0i Chain A

Receptor sequence
>7y0iA (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
SGGRDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCD
PRPVDR
3D structure
PDB7y0i Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.359: [histone H3]-lysine(36) N-trimethyltransferase.
2.1.1.367: [histone H3]-lysine(9) N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D16 E17 G18 L19 M20 I21 W29 T39 V41 D16 E17 G18 L19 M20 I21 W29 T39 V41
BS02 ZN A C9 C11 H31 C34 C9 C11 H31 C34
BS03 ZN A C23 C26 C46 C49 C23 C26 C46 C49
External links
PDB RCSB:7y0i, PDBe:7y0i, PDBj:7y0i
PDBsum7y0i
PubMed36033518
UniProtQ9NR48|ASH1L_HUMAN Histone-lysine N-methyltransferase ASH1L (Gene Name=ASH1L)

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