Structure of PDB 7y0f Chain A

Receptor sequence
>7y0fA (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
NSGIECDTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKS
WHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSIY
KKLYHSDACSSKAVVSLRCIACGVNLND
3D structure
PDB7y0f Crystal structure of TMPRSS2 in complex with UK-371804
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.122: transmembrane protease serine 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N131 D134 V136 H138 D144 E145 N14 D17 V19 H21 D27 E28
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7y0f, PDBe:7y0f, PDBj:7y0f
PDBsum7y0f
PubMed37990007
UniProtO15393|TMPS2_HUMAN Transmembrane protease serine 2 (Gene Name=TMPRSS2)

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