Structure of PDB 7y0e Chain A

Receptor sequence
>7y0eA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
NSGIECDCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSW
HPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAVD
IYKKLYHSDACSSKAVVSLRCIACGVNLND
3D structure
PDB7y0e Crystal structure of TMPRSS2 in complex with Camostat
ChainA
Resolution2.39 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.21.122: transmembrane protease serine 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N131 D134 V136 H138 D144 E145 N13 D16 V18 H20 D26 E27
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7y0e, PDBe:7y0e, PDBj:7y0e
PDBsum7y0e
PubMed37990007
UniProtO15393|TMPS2_HUMAN Transmembrane protease serine 2 (Gene Name=TMPRSS2)

[Back to BioLiP]